Association of Patient Controlled Analgesia and Total Inpatient Opioid Use After Pancreatectomy

Autor: Russell G. Witt, Timothy E. Newhook, Laura R. Prakash, Morgan L. Bruno, Elsa M. Arvide, Whitney L. Dewhurst, Naruhiko Ikoma, Jessica E. Maxwell, Michael P. Kim, Jeffrey E. Lee, Matthew H.G. Katz, Ching-Wei D. Tzeng
Rok vydání: 2022
Předmět:
Zdroj: J Surg Res
ISSN: 0022-4804
Popis: OBJECTIVES: The initial settings on an intravenous patient-controlled analgesia (IV-PCA) pump can represent a significant source of postoperative opioid exposure. The primary aim of this study was to evaluate the impact of first day IV-PCA use on total inpatient opioid use after open pancreatectomy, before and after standardization of initial dosing. METHODS: Inpatient oral morphine equivalents (OME) were reviewed for pancreatectomy patients treated with IV-PCA at a single institution before and after (3/2016–8/2017 vs. 3/2019–11/2020) implementation of a standardized initial IV-PCA dosing regimen (initial limit 0.1mg hydromorphone, or 1mg OME, every 10 min as needed). IV-PCA OME in the first 24 hours and total inpatient OME were compared between cohorts. RESULTS: Of 220 total patients, 132 were in the pre-standardization historical cohort. First-24-hour IV-PCA use was different (pre-standardization median 95mg vs. post-standardization 15mg, p
Databáze: OpenAIRE