Full‐term newborn infant with blistering skin lesions—Caution regarding use of pain medications
| Autor: | Melinda Sanders, Aamir Hussain, Naveed Hussain, Clare O. Riotte |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Mastocytosis Cutaneous Multiple Organ Failure Blistering skin Dermatology 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound Fatal Outcome 0302 clinical medicine Humans Medicine Neonatology Full Term Morphine integumentary system business.industry Infant Newborn Degranulation Infant newborn Analgesics Opioid chemistry 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health business Skin lesion Histamine medicine.drug |
| Zdroj: | Pediatric Dermatology. 36:362-364 |
| ISSN: | 1525-1470 0736-8046 |
| DOI: | 10.1111/pde.13794 |
| Popis: | Multiple opioids are known to trigger mast cell degranulation. We report the case of a neonate with blistering skin lesions at birth who died of multi-organ failure after administration of morphine. Given the excessive histamine release and potential complications associated with morphine administration, alternative opioids and adjuvants should be considered in infants presenting with evidence of bullous or infiltrative skin lesions until mastocytosis is ruled out. |
| Databáze: | OpenAIRE |
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