Effect of Liver Cirrhosis on the Outcomes of Peritoneal Dialysis
| Autor: | Dong Ki Kim, Kook Hwan Oh, Seung Seok Han, Yon Su Kim, Young Lee Jung, Chung Sik Lee, Chun Soo Lim, Jae Yoon Park |
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| Rok vydání: | 2018 |
| Předmět: |
Liver Cirrhosis
Male medicine.medical_specialty Cirrhosis medicine.medical_treatment Biopsy Peritonitis Gastroenterology Peritoneal dialysis Internal medicine medicine Humans Treatment Failure Dialysis Retrospective Studies Ultrasonography Catheter insertion business.industry Mortality rate Hazard ratio General Medicine Middle Aged medicine.disease Prognosis Magnetic Resonance Imaging Nephrology Kidney Failure Chronic Female Hemodialysis business Tomography X-Ray Computed Peritoneal Dialysis Follow-Up Studies |
| Zdroj: | Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 39(6) |
| ISSN: | 1718-4304 |
| Popis: | Background Peritoneal dialysis (PD) has become an increasingly important treatment modality for end-stage renal disease. However, application of PD in patients with liver cirrhosis (LC) and subsequent outcomes have not been thoroughly evaluated. Methods A total of 1,366 patients (≥ 18 years old) who started PD at 4 tertiary referral centers between January 2000 and December 2015 were initially reviewed. Among them, 45 patients with LC were finally analyzed (LC-PD). Using the multivariate Cox hazard ratio (HR) model, outcomes such as technique failure, infection, and mortality in patients with LC-PD were compared with those in non-LC-PD patients (non-LC-PD) or patients with LC who received hemodialysis (LC-HD). All of the patients were selected by 1:1 matching of age, sex, catheter insertion date, and diabetes mellitus. Results During the mean follow-up duration of 43 ± 35.8 months, 12 patients with LC-PD experienced technique failure, and this rate was similar to that of non-LC-PD patients. In evaluating infection episodes, the most common causes for peritonitis and exit-site infection were Escherichia coli (5.8%) and Staphylococcus aureus (19.3%), respectively; these event rates of LC-PD did not differ from those of non-LC-PD. The all-cause mortality rate of the LC-PD group was not different from that of the non-LC-PD and LC-HD groups. Conclusion Dialysis outcomes such as technique failure, infection, and mortality are not affected by the presence of LC. Accordingly, PD therapy is a good option in patients with LC. |
| Databáze: | OpenAIRE |
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