The Prevalence of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, and Bacteroides forsythus in Humans 1 Year After 4 Randomized Treatment Modalities
| Autor: | Mark R. Patters, John W. Dean, Jacob Shiloah, Paul Bland, Gilbert Toledo |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Male Gingival and periodontal pocket Bleeding on probing Colony Count Microbial Dentistry Aggregatibacter actinomycetemcomitans Citric Acid Surgical Flaps Root Planing Scaling and root planing Periodontal Attachment Loss Prevalence medicine Bacteroides Humans Periodontal Pocket Gingival Recession Periodontitis Gingival recession Chelating Agents biology business.industry Dental Plaque Index Chlorhexidine Gingival Crevicular Fluid Middle Aged Alveolectomy biology.organism_classification Treatment Outcome Clinical attachment loss Actinobacillus Dental Scaling Periodontics Female Periodontal Index medicine.symptom Gingival Hemorrhage business Porphyromonas gingivalis Follow-Up Studies medicine.drug |
| Zdroj: | Journal of Periodontology. 69:1364-1372 |
| ISSN: | 1943-3670 0022-3492 |
| DOI: | 10.1902/jop.1998.69.12.1364 |
| Popis: | The relationship between probing attachment changes in treated periodontal pockets and the prevalence of selected periodontal pathogens was assessed in 10 patients with adult periodontitis 1 year following randomized therapy. All patients had at least 1 tooth in each quadrant with an inflamed pocket of probing depth > or =5 mm and clinical attachment loss and harbored at least one of the following 3 major periodontal pathogens: Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, or Bacteroides forsythus. The number of target organisms per site was determined preoperatively; at 1 week; and at 1, 3, 6, and 12 months postoperatively utilizing DNA probes. The following clinical parameters were measured and recorded preoperatively and at 1, 3, 6, and 12 months post-treatment: gingival fluid flow, gingival index, plaque index, probing depth, probing attachment level, gingival recession, and bleeding on probing. One quadrant in each patient was randomly assigned to 1 of the following 4 treatments: 1) scaling and root planing; 2) pocket reduction through osseous surgery and apically-positioned flap; 3) modified Widman flap; and 4) modified Widman flap and topical application of saturated citric acid at pH 1 for 3 minutes. All 4 treatments were rendered in one appointment using local anesthesia. No postoperative antibiotics were used, but patients rinsed with 0.12% chlorhexidine for the first 3 months postoperatively and received a prophylaxis every 3 months. This investigation revealed: 1) 30.0% of the sites were infected by at least 1 species at 3, 6, and 12 months postoperatively. 2) Failing sites were infected by a high number of both Pg and Bf These sites had a mean of 24.2+/-9.0 x 10(3) Pg and 93.1+/-42.0 X 10(3) Bf while stable sites had a mean of 6.8+/-0.5 x 10(3) Pg and 7.2+/-1.2 x 10(3) Bf (P = 0.06 and P = 0.05, respectively). 3) The infected sites lost significantly more mean clinical attachment at 12 months (1.5+/-0.5 mm compared to a loss of 0.2+/-0.3 mm for uninfected sites, P = 0.017). 4) The infected sites had a significantly greater BOP (67+/-14% versus 25+/-8% for uninfected sites at 12 months, P = 0.012). 5) The choice of treatment modality did not affect the prevalence of the target species at 1 year post-treatment. These results suggest that prevalence of microbial pathogens negatively affects the 1 year outcome of periodontal surgical and nonsurgical therapy. |
| Databáze: | OpenAIRE |
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