Supplemental Figures 1 through 14 from A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells

Autor: Didier Merlin, Emilie Viennois, Zhan Zhang, Yuchen Zhang, Jun Zhou, Bo Xiao, Moon Kwon Han, Liuqing Wen, Changlong Xu, Mingzhen Zhang
Rok vydání: 2023
Popis: Adsorption/desorption isotherms and pore size distributions of MSN-NH2 (S1). FITR spectra of MSN-NH2 and MSN-destriobiotin (S2). DLS and TEM characterizations of MSN-HA/Dox (S3). Figures of MSN-HA loaded with rhodamine B (S4). Release profiles of Dox in MSN-HA/Dox under neutral buffer (pH 7.0) (S5). The co-localization of MSN-HA/rhodamine B with the endocytosis marker (S6). In vitro compatibilities investigated by MTT and ATPlite assays (S7). In vivo biocompatibility evaluation of MSN-HA (S8). Fluorescence images of Colon-26 and HT-29 cells incubated with Dox and MSN-HA/Dox (S9). MSN-HA/Dox induced apoptosis in vitro (S10). Interaction of MSN-HA with proteins and blood cells (S11). Immunological analysis of MSN-HA and MSN-HA/Dox (S12). Histological analysis of tumor tissues (S13). Times-dependent biodistribution of MSN-HA (S14).
Databáze: OpenAIRE