The psychological impact of disclosing amyloid status to Japanese elderly: a preliminary study on asymptomatic patients with subjective cognitive decline
| Autor: | Taisei Wake, Takahito Yoshizaki, Kei Funaki, Daisuke Ito, Koji Murakami, Masaru Mimura, Hajime Tabuchi, Tadaki Nakahara, Masashi Kameyama, Masahiro Jinzaki, Bun Yamagata |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Disclosure Anxiety Neuropsychological Tests Asymptomatic 03 medical and health sciences 0302 clinical medicine Japan Alzheimer Disease medicine Humans Dementia Cognitive decline Psychiatry Depression (differential diagnoses) Aged Aged 80 and over Amyloid beta-Peptides 030214 geriatrics Depression business.industry Brain medicine.disease Psychiatry and Mental health Clinical Psychology Distress Mood Positron-Emission Tomography Female Geriatrics and Gerontology Alzheimer's disease medicine.symptom business Gerontology 030217 neurology & neurosurgery Clinical psychology |
| Zdroj: | International Psychogeriatrics. 30:635-639 |
| ISSN: | 1741-203X 1041-6102 |
| DOI: | 10.1017/s1041610217002204 |
| Popis: | In Japan, 4.6 million people are living with dementia and the number is expected to rise to 7 million by 2025. Amyloid-β (Aβ) positron emission tomography (PET) is used for cognitively normal Japanese people with or without subjective cognitive decline (SCD) for the purpose of clinical trials or diagnosis. Nevertheless, no empirical studies have been conducted on the safety of disclosing amyloid status to such populations. We conducted amyloid PET imaging on 42 participants (Aβ positive (n = 10) and negative (n = 32)). State anxiety and depression were measured at pre- and post-disclosure, and test-related distress at post-disclosure. Mean state anxiety and depression scores were below the cut-off through pre- and post-disclosure in the Aβ positive and negative groups. State anxiety and depression did not change over time and were not different between groups. Mean test-related distress scores were within normal limits at post-disclosure in both groups. No significant difference was found between groups. Disclosing Aβ positive results did not cause greater mood disturbance than negative results in a short period of time. The short-term psychological safety of disclosing Aβ PET results to asymptomatic Japanese adults with SCD was indicated. |
| Databáze: | OpenAIRE |
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