Micro/Nanorobot: A Promising Targeted Drug Delivery System
| Autor: | Weien Yuan, Wenwei Mao, Mengyi Hu, Xuan Chen, Xuemei Ge, Xiuping Qian |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
cell-based micro/nanorobot
Computer science endogenous power Pharmaceutical Science lcsh:RS1-441 Nanotechnology 02 engineering and technology Surgical operation Review 010402 general chemistry 01 natural sciences micro/nanorobot targeted drug delivery exogenous power lcsh:Pharmacy and materia medica Light energy Acoustic field Medical treatment 021001 nanoscience & nanotechnology 0104 chemical sciences Targeted drug delivery Blood circulation Drug delivery Nanorobotics DNA origami 0210 nano-technology |
| Zdroj: | Pharmaceutics, Vol 12, Iss 665, p 665 (2020) Pharmaceutics |
| ISSN: | 1999-4923 |
| Popis: | Micro/nanorobot, as a research field, has attracted interest in recent years. It has great potential in medical treatment, as it can be applied in targeted drug delivery, surgical operation, disease diagnosis, etc. Differently from traditional drug delivery, which relies on blood circulation to reach the target, the designed micro/nanorobots can move autonomously, which makes it possible to deliver drugs to the hard-to-reach areas. Micro/nanorobots were driven by exogenous power (magnetic fields, light energy, acoustic fields, electric fields, etc.) or endogenous power (chemical reaction energy). Cell-based micro/nanorobots and DNA origami without autonomous movement ability were also introduced in this article. Although micro/nanorobots have excellent prospects, the current research is mainly based on in vitro experiments; in vivo research is still in its infancy. Further biological experiments are required to verify in vivo drug delivery effects of micro/nanorobots. This paper mainly discusses the research status, challenges, and future development of micro/nanorobots. |
| Databáze: | OpenAIRE |
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