Short‐range regulatory chromatin loops in plants
| Autor: | Pablo Andrés Manavella, Delfina Gagliardi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
0301 basic medicine Euchromatin Physiology Heterochromatin SHORT-RANGE CHROMATIN INTERACTIONS High resolution Plant Science Computational biology Biology 01 natural sciences Genome SMALL RNAS purl.org/becyt/ford/1 [https] 03 medical and health sciences Gene Expression Regulation Plant Gene expression purl.org/becyt/ford/1.6 [https] DNA METHYLATION CHROMATIN LOOPS Plants GENOME TOPOLOGY Chromatin 030104 developmental biology DNA methylation CHROMATIN STRUCTURE 010606 plant biology & botany |
| Zdroj: | CONICET Digital (CONICET) Consejo Nacional de Investigaciones Científicas y Técnicas instacron:CONICET |
| ISSN: | 1469-8137 0028-646X |
| DOI: | 10.1111/nph.16632 |
| Popis: | In all eukaryotic organisms, gene expression correlates with the condensation state of the chromatin. Highly packed genome regions, known as heterochromatins, are associated with repressed loci, whereas euchromatic regions represent a relaxed state of the chromatin actively transcribed. However, even in these active regions, associations between chromatin domains dynamically modify genome topology and alter gene expression. Long-range interaction within and between chromosomes determines chromatin domains that help to coordinate transcriptional events. On the other hand, short-range chromatin interactions emerged as dynamic mechanisms regulating the expression of specific loci. Our current capacity to decipher genome topology at high resolution allowed us to identify numerous cases of short-range regulatory chromatin interactions, which are reviewed in this Insight article. Fil: Gagliardi, Delfina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina Fil: Manavella, Pablo Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina |
| Databáze: | OpenAIRE |
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