Plaque Character and Progression According to the Location of Coronary Atherosclerotic Plaque
| Autor: | A. Maxim Bax, Umberto Gianni, Filippo Cademartiri, Donghee Han, Yao Lu, Sang Eun Lee, Xiaoyue Ma, Ji Min Sung, Gianluca Pontone, Edoardo Conte, Hugo Marques, Mouaz H. Al-Mallah, Benjamin Goebel, Matthew J. Budoff, Jonathon Leipsic, Ilan Gottlieb, Kavitha Chinnaiyan, Leslee J. Shaw, Daniele Andreini, Jung Hyun Choi, Byoung Kwon Lee, Eun Ju Chun, Martin Hadamitzky, Hyuk Jae Chang, Erica Maffei, Yong Jin Kim, Sanghoon Shin, Benjamin C. Lee, Fay Y. Lin, Jagat Narula, Yeonyee E. Yoon, Pedro de Araújo Gonçalves |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Acute coronary syndrome Computed Tomography Angiography Coronary Artery Disease Culprit Cohort Studies Plaque volume Internal medicine medicine Humans Registries Aged business.industry Coronary computed tomography angiography Mean age Middle Aged medicine.disease Plaque Atherosclerotic Lumen Diameter medicine.anatomical_structure Disease Progression Cardiology Female Cardiology and Cardiovascular Medicine business Artery |
| Zdroj: | The American Journal of Cardiology. 158:15-22 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/j.amjcard.2021.07.040 |
| Popis: | Although acute coronary syndrome culprit lesions occur more frequently in the proximal coronary artery, whether the proximal clustering of high-risk plaque is reflected in earlier-stage atherosclerosis remains unclarified. We evaluated the longitudinal distribution of stable atherosclerotic lesions on coronary computed tomography angiography (CCTA) in 1,478 patients (mean age, 61 years; men, 58%) enrolled from a prospective multinational registry of consecutive patients undergoing serial CCTA. Of 3,202 coronary artery lesions identified, 2,140 left lesions were classified (based on the minimal lumen diameter location) into left main (LM, n = 128), proximal (n = 739), and other (n = 1,273), and 1,062 right lesions were classified into proximal (n = 355) and other (n = 707). Plaque volume (PV) was the highest in proximal lesions (median, 26.1 mm3), followed by LM (20.6 mm3) and other lesions (15.0 mm3, p |
| Databáze: | OpenAIRE |
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