SEASONALITY, PARASITE DIVERSITY, AND LOCAL EXTINCTIONS INPLASMODIUM FALCIPARUMMALARIA

Autor:	William H. Bossert, Gerry F. Killeen, John C. Beier, F. Ellis McKenzie
Rok vydání:	2001
Předmět:	Extinction Ecology Anopheles Plasmodium falciparum Biology biology.organism_classification medicine.disease Article law.invention Transmission (mechanics) law Local extinction Vector (epidemiology) parasitic diseases medicine Parasite hosting Ecology Evolution Behavior and Systematics Malaria
Zdroj:	Ecology. 82:2673-2681
ISSN:	0012-9658
DOI:	10.1890/0012-9658(2001)082[2673:spdale]2.0.co;2
Popis:	We incorporate stochastic, density-dependent seasonal recruitment in adult Anopheles mosquito populations in a discrete-event model of Plasmodium falciparum malaria transmission and find the probabilities of parasite extinction higher than with perennial transmission. Seasonal fluctuations in vector populations act to synchronize the dynamics of infection and immunity in host populations, leading to fluctuations in parasite prevalence greater than expected solely on the basis of high- and low-season vector densities. This synchronization also biases frequencies of infection with multiple parasite phenotypes or genotypes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7609c4255372708b948e443c2c4708 https://doi.org/10.1890/0012-9658(2001)082[2673:spdale]2.0.co Zobrazit plný text záznamu Plný text