Sun exposure and melanoma prognostic factors
| Autor: | Ketty Peris, Rosachiara Forcignanò, Lucia Benedetto, Vincenzo De Giorgi, Maria Teresa Corradin, Paola Queirolo, Giuseppe Giudice, Francesco Spagnolo, Antonella Vecchiato, Paolo A. Ascierto, Sara Gandini, Alessandro Testori, Carlo Riccardo Rossi, Fabrizio Ayala, Giusto Trevisan, Guido Zannetti, Giovanni Borroni, Giulio Tosti, Maurizio Montella |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Cancer Research
medicine.medical_specialty sunbed Breslow Thickness sun exposure 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine melanoma medicine Family history Sunlight business.industry Melanoma Fitzpatrick Skin Type I Confounding Breslow thickness prognosis ulceration Cancer Articles medicine.disease Dermatology Surgery Oncology 030220 oncology & carcinogenesis Cutaneous melanoma Prognosis Sun exposure Sunbed Ulceration Settore MED/35 - MALATTIE CUTANEE E VENEREE business |
| Zdroj: | Oncology Letters |
| ISSN: | 1792-1082 1792-1074 |
| Popis: | Previous studies have reported an association between sun exposure and the increased survival of patients with cutaneous melanoma (CM). The present study analyzed the association between ultraviolet (UV) light exposure and various prognostic factors in the Italian Clinical National Melanoma Registry. Clinical and sociodemographic features were collected, as well as information concerning sunbed exposure and holidays with sun exposure. Analyses were performed to investigate the association between exposure to UV and melanoma prognostic factors. Between December 2010 and December 2013, information was obtained on 2,738 melanoma patients from 38 geographically representative Italian sites. A total of 49% of the patients were >55 years old, 51% were men, 50% lived in the north of Italy and 57% possessed a high level of education (at least high school). A total of 8 patients had a family history of melanoma and 56% had a fair phenotype (Fitzpatrick skin type I or II). Of the total patients, 29% had been diagnosed with melanoma by a dermatologist; 29% of patients presented with a very thick melanoma (Breslow thickness, >2 mm) and 25% with an ulcerated melanoma. In total, 1% of patients had distant metastases and 13% exhibited lymph node involvement. Holidays with sun exposure 5 years prior to CM diagnosis were significantly associated with positive prognostic factors, including lower Breslow thickness (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|