Molecularly Imprinted Nanospheres by Nonaqueous Emulsion Polymerization
| Autor: | Markus Klapper, Klaus Müllen, Gita Dvorakova, Andrea Biffis, Robert Haschick, Khalid Chiad |
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| Rok vydání: | 2010 |
| Předmět: |
chemistry.chemical_classification
Materials science Polymers and Plastics Organic Chemistry Dispersity Molecularly imprinted polymer Emulsion polymerization emulsion polymerization molecular imprinting propranolol molecular recognition macromolecular substances Polymer chemistry.chemical_compound Monomer chemistry Chemical engineering Methacrylic acid Polymer chemistry Materials Chemistry Particle size Molecular imprinting |
| Zdroj: | Macromolecular Rapid Communications. 31:2035-2040 |
| ISSN: | 1022-1336 |
| DOI: | 10.1002/marc.201000406 |
| Popis: | The preparation of nanosized, molecularly imprinted polymer particles by nonaqueous emulsion polymerization is presented. Monodisperse cross-linked polymer nanospheres with a diameter of around 100 nm were synthesized using a standard monomer mixture of methacrylic acid and ethylene dimethacrylate, containing (±)-propranolol as a template. The rebinding efficiency of the resulting particles was determined by batch rebinding tests and isothermal titration calorimetry (ITC). The results indicate that the proposed imprinting process under nonaqueous conditions lead to particles with an enhanced capacity of template rebinding compared to both nonimprinted ones and to particles obtained by more conventional emulsion polymerization in water. |
| Databáze: | OpenAIRE |
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