Effect of 17 beta estradiol on [3H] progesterone binding in rat brain
| Autor: | Vera H. Kruczak, William A. Prass, Virinder K. Moudgil |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment General Biochemistry Genetics and Molecular Biology Chromatography Affinity Steroid Text mining Cytosol Internal medicine medicine Animals Castration General Pharmacology Toxicology and Pharmaceutics Progesterone Cerebral Cortex Estradiol business.industry Chemistry Uterus General Medicine Rat brain Rats Endocrinology Female business Receptors Progesterone |
| Zdroj: | Life sciences. 25(15) |
| ISSN: | 0024-3205 |
| Popis: | A progesterone-binding component is reported in the cerebral hemispheres of immature female rat. [3H] progesterone binding in the brain cytosol is increased following two weeks of estradiol administration. The [3H] progesterone binding by this component can be reduced by pretreatment with unlabeled steroid. In addition, the binder from both control and estradiol-treated groups shows inter-action with ATP immobilized on columns of ATP-Sepharose. |
| Databáze: | OpenAIRE |
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