Molecular diagnosis of Fusobacterium necrophorum infection (Lemierre?s syndrome)
| Autor: | H. Zhang, Patrick F.K. Yong, R. K. Marriott, H. Ludlam, S. H. Aliyu, M. D. Curran, Melanie J. Newport |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
DNA Bacterial Male Microbiology (medical) medicine.medical_specialty Pathology Microbiological culture Pcr assay ved/biology.organism_classification_rank.species Polymerase Chain Reaction law.invention Medical microbiology law Lemierre's syndrome Fusobacterium necrophorum medicine Humans Brain abscess Polymerase chain reaction biology ved/biology business.industry Syndrome General Medicine medicine.disease biology.organism_classification Infectious Diseases Fusobacterium Fusobacterium Infections business |
| Zdroj: | European Journal of Clinical Microbiology & Infectious Diseases. 24:226-229 |
| ISSN: | 1435-4373 0934-9723 |
| DOI: | 10.1007/s10096-005-1298-6 |
| Popis: | Presented here is the case of a 27-year-old male with atypical features of Lemierre's syndrome in which a definitive diagnosis was achieved using molecular methods. While routine investigations, including bacterial cultures, were unhelpful, two real-time PCR assays demonstrated Fusobacterium necrophorum-specific DNA in aspirates from brain and renal abscesses. This is the first report demonstrating that a laboratory diagnosis can be made using molecular methods in suspected cases of Lemierre's syndrome. Use of these methods can thus resolve diagnostic confusion, prevent unnecessary investigation, and direct specific antimicrobial treatment. |
| Databáze: | OpenAIRE |
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