The contraceptive potential of Carica papaya seed on oestrus cycle, progesterone, and histomorphology of the Utero-ovarian tissue of adult wistar rats
| Autor: | Memudu Ae, Tayo Jane Oluwole |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
endocrine system
Ovary Biology progesterone Andrology Contraceptive Agents medicine Animals Rats Wistar Estrous cycle Carica papaya Carica Plant Extracts Ovarian tissue Mucin oestrus cycle biology.organism_classification Rats medicine.anatomical_structure Theca In utero Seeds Original Article Corpus luteum utero-ovarian tissue |
| Zdroj: | JBRA Assisted Reproduction |
| ISSN: | 1518-0557 1517-5693 |
| Popis: | Objective: The study’s goal was to ascertain the contraceptive effects of Aqueous extract of Carica papaya on female rats by assessing changes in the body weight, estrous cycle, serum progesterone level and the cyto-architecture of the Utero-ovarian tissue. Methods: We used twenty (20) healthy young Adult Female Albino rats. The study ran for 7 and 21 days, respectively. Each study group has their Experimental (treated 200mg/kg aqueous extract of Carica papaya seed extract) and Control group (n=5). We determined daily the phases and frequencies of the estrous cycles of the rats during the administration of the extract. We processed the utero-ovarian tissue for histological analysis, and we assessed serum progesterone level and the oestrus cycle pattern. Results: There was a significant increase in body and Ovarian weights after 21 days of treatment when compared to controls and those treated for 7 days. However, uterine weight reduced significantly (p |
| Databáze: | OpenAIRE |
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