N-Doped Reduced Graphene Oxide/Gold Nanoparticles Composite as an Improved Sensing Platform for Simultaneous Detection of Dopamine, Ascorbic Acid, and Uric Acid
| Autor: | Zoraida González, Daria Minta, Piotr Wiench, Stanisław Gryglewicz, Grażyna Gryglewicz |
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| Přispěvatelé: | Ministry of Science and Higher Education (Poland) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
Letter Oxide Metal Nanoparticles 02 engineering and technology Ascorbic Acid 010402 general chemistry lcsh:Chemical technology 01 natural sciences Biochemistry Analytical Chemistry law.invention chemistry.chemical_compound Simultaneous detection law Nitrogen-doped reduced graphene oxide Gold nanoparticles lcsh:TP1-1185 Electrical and Electronic Engineering Instrumentation Electrodes Detection limit Graphene Electrochemical Techniques 021001 nanoscience & nanotechnology Ascorbic acid Atomic and Molecular Physics and Optics 0104 chemical sciences Electrochemical gas sensor Uric Acid chemistry Electrochemical sensor Colloidal gold Dopamin Graphite Differential pulse voltammetry Gold Cyclic voltammetry dopamine 0210 nano-technology Interference Nuclear chemistry |
| Zdroj: | Sensors, Vol 20, Iss 4427, p 4427 (2020) Digital.CSIC. Repositorio Institucional del CSIC instname Sensors (Basel, Switzerland) |
| Popis: | Gold nanoparticles (AuNPs) were homogeneously electrodeposited on nitrogen-doped reduced graphene oxide (N-rGO) to modify a glassy carbon electrode (GCE/N-rGO-Au) in order to improve the simultaneous detection of dopamine (DA), ascorbic acid (AA), and uric acid (UA). N-rGO was prepared by the hydrothermal treatment of graphene oxide (GO) and urea at 180 °C for 12 h. AuNPs were subsequently electrodeposited onto the surface of GCE/N-rGO using 1 mM HAuCl4 solution. The morphology and chemical composition of the synthesized materials were characterized by field-emission scanning electron microscopy and X-ray photoelectron spectroscopy. The electrochemical performance of the modified electrodes was investigated through cyclic voltammetry and differential pulse voltammetry measurements. Compared to GCE/rGO-Au, GCE/N-rGO-Au exhibited better electrochemical performance towards the simultaneous detection of the three analytes due to the more homogeneous distribution of the metallic nanoparticles as a result of more efficient anchoring on the N-doped areas of the graphene structure. The GCE/N-rGO-Au-based sensor operated in a wide linear range of DA (3–100 µM), AA (550–1500 µM), and UA (20–1000 µM) concentrations with a detection limit of 2.4, 58, and 8.7 µM, respectively, and exhibited satisfactory peak potential separation values of 0.34 V (AA-DA), 0.20 V, (DA-UA) and 0.54 V (AA-UA). Remarkably, GCE/N-rGO-Au showed a very low detection limit of 385 nM towards DA, not being susceptible to interference, and maintained 90% of its initial electrochemical signal after one month, indicating an excellent long-term stability. This research was financially supported by a statutory activity subsidy from the Polish Ministry of Science and Higher Education for the Faculty of Chemistry of Wrocław University of Science and Technology. |
| Databáze: | OpenAIRE |
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