A study on the efficacy of intraventricular urokinase in the treatment of intraventricular haemorrhage
| Autor: | M. Y. Y. Tung, P. L. Ong, W. T. Seow, K. K. Tan |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Male medicine.medical_specialty Randomization medicine.medical_treatment Cerebral Ventricles Ventriculostomy Central nervous system disease Ventriculitis medicine Humans Thrombolytic Therapy Aged Cerebral Hemorrhage Aged 80 and over Urokinase Chemotherapy business.industry Vascular disease General Medicine Middle Aged medicine.disease Urokinase-Type Plasminogen Activator Surgery Hydrocephalus Treatment Outcome Anesthesia Female Neurology (clinical) Tomography X-Ray Computed business Follow-Up Studies medicine.drug External ventricular drain |
| Zdroj: | British Journal of Neurosurgery. 12:234-239 |
| ISSN: | 1360-046X 0268-8697 |
| Popis: | Twenty-one patients with intraventricular haemorrhage were randomized to two treatment groups. Both groups had bilateral external ventricular drains inserted, but only the treatment group received 50,000 IU urokinase instilled into the ventricles. The clinical and radiological progress, and 1- and 6-month outcomes were compared. The group that received urokinase treatment was shown to have an improved outcome, with a lower mortality and a lower incidence of hydrocephalus requiring shunt insertion. No haemorrhagic complications were seen in either group, although the treatment group had a slightly increased rate of drain-related ventriculitis. |
| Databáze: | OpenAIRE |
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