Hybrid FDG-PET/MR compared to FDG-PET/CT in adult lymphoma patients
| Autor: | Victorine V. Muse, Ciprian Catana, Alexander R. Guimaraes, Ephraim P. Hochberg, Grae Arabasz, Jeffrey A. Barnes, Jeremy S. Abramson, Onofrio A. Catalano, Michael A. Blake, Bruce R. Rosen, Martin J. Shelly, Wendy Atkinson, S. McDermott |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Urology Multimodal Imaging 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 Positron Emission Tomography Computed Tomography Image Interpretation Computer-Assisted medicine Effective diffusion coefficient Humans Radiology Nuclear Medicine and imaging In patient Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Lymphoma Non-Hodgkin Adult Lymphoma Gastroenterology Middle Aged medicine.disease Hodgkin Disease Lymphoma Diffusion Magnetic Resonance Imaging Positron emission tomography 030220 oncology & carcinogenesis Positron-Emission Tomography Fdg pet ct Female Radiology Radiopharmaceuticals business Nuclear medicine Correction for attenuation Diffusion MRI |
| Zdroj: | Abdominal radiology (New York). 41(7) |
| ISSN: | 2366-0058 |
| Popis: | The goal of this study is to evaluate the diagnostic performance of simultaneous FDG-PET/MR including diffusion compared to FDG-PET/CT in patients with lymphoma. Eighteen patients with a confirmed diagnosis of non-Hodgkin’s (NHL) or Hodgkin’s lymphoma (HL) underwent an IRB-approved, single-injection/dual-imaging protocol consisting of a clinical FDG-PET/CT and subsequent FDG-PET/MR scan. PET images from both modalities were reconstructed iteratively. Attenuation correction was performed using low-dose CT data for PET/CT and Dixon-MR sequences for PET/MR. Diffusion-weighted imaging was performed. SUVmax was measured and compared between modalities and the apparent diffusion coefficient (ADC) using ROI analysis by an experienced radiologist using OsiriX. Strength of correlation between variables was measured using the Pearson correlation coefficient (r p). Of the 18 patients included in this study, 5 had HL and 13 had NHL. The median age was 51 ± 14.8 years. Sixty-five FDG-avid lesions were identified. All FDG-avid lesions were visible with comparable contrast, and therefore initial and follow-up staging was identical between both examinations. SUVmax from FDG-PET/MR [(mean ± sem) (21.3 ± 2.07)] vs. FDG-PET/CT (mean 23.2 ± 2.8) demonstrated a strongly positive correlation [r s = 0.95 (0.94, 0.99); p |
| Databáze: | OpenAIRE |
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