Surgical management of spinal intramedullary tumors: Ten-year experience in a single institution
Autor: | Cihan Isler, Mehmet Hanci, Osman Kizilkilic, Orkhan Alizada, Mehmet Yigit Akgun, Rahsan Kemerdere, Mustafa Onur Ulu |
---|---|
Rok vydání: | 2020 |
Předmět: |
Adult
Male Ependymoma medicine.medical_specialty medicine.medical_treatment Neurosurgical Procedures law.invention Intramedullary rod 03 medical and health sciences 0302 clinical medicine law Physiology (medical) Hemangioblastoma Biopsy medicine Humans Spinal Cord Neoplasms Pathological Retrospective Studies Chemotherapy medicine.diagnostic_test business.industry Astrocytoma General Medicine Middle Aged medicine.disease Spinal cord Surgery Treatment Outcome medicine.anatomical_structure Neurology 030220 oncology & carcinogenesis Female Neurology (clinical) business 030217 neurology & neurosurgery |
Zdroj: | Journal of Clinical Neuroscience. 73:201-208 |
ISSN: | 0967-5868 |
Popis: | Despite their rare occurrence, intramedullary spinal cord tumors can cause considerable morbidity and mortality without treatment. Timing of surgery, extent of resection and selection of favorable treatment option are important considerations for a good surgical outcome. In this clinical study, we report our patient series and convey our treatment strategy. We retrospectively reviewed 91 patients with primary intramedullary spinal cord tumors who underwent microsurgical resection at our institution between 2008 and 2018. Data were collected consisting of age, sex, location and histology of tumor, extent of resection, presenting symptoms and neurological outcomes. Modified McCormick Scale was used to assess neurological status of patients. 47 female and 44 male patients were followed-up for a mean period of 35.7 months. The most frequent pathological diagnosis was ependymoma in 56 patients, followed by astrocytoma in 21 and hemangioblastoma in 5 patients. The rest of the tumors consisted of 3 cavernomas, 3 mature cystic teratomas, 2 PNET, one epidermoid tumor. Gross total resection was achieved in 67 patients, while subtotal resection and biopsy was performed in 15 and 9 respectively. The most commonly involved localization was cervical (n = 39), followed by thoracic region (n = 24). Despite immediate postoperative worsening of neurological status, a great number of patients improved at the last follow-up. Gross total resection remains the primary goal of treatment while adjuvant radiation and/or chemotherapy may be alternative options for high grade tumors. Preoperative neurological status was the most important and the strongest predictor of functional outcome. |
Databáze: | OpenAIRE |
Externí odkaz: |