Frequency and clinical profile of patients with polycystic kidney disease in southern Brazil

Autor: Daiana Benck Porsch, Elvino José Guardão Barros, Vagner Milani, Ane Cláudia Fernandes Nunes, Liana Bertolin Rossato, Israel Roisenberg, Cristiane Bastos de Mattos
Rok vydání: 2008
Předmět:
Nephrology
Adult
Male
medicine.medical_specialty
medicine.medical_treatment
Population
Autosomal dominant polycystic kidney disease
urologic and male genital diseases
Critical Care and Intensive Care Medicine
Kidney Function Tests
Risk Assessment
Severity of Illness Index
Statistics
Nonparametric
End stage renal disease
Age Distribution
Renal Dialysis
Internal medicine
Polycystic kidney disease
Medicine
Humans
Multicenter Studies as Topic
Sex Distribution
education
Probability
education.field_of_study
Analysis of Variance
urogenital system
business.industry
Medical record
Incidence
General Medicine
Middle Aged
medicine.disease
Polycystic Kidney
Autosomal Dominant
Prognosis
Survival Analysis
female genital diseases and pregnancy complications
Surgery
Cross-Sectional Studies
Treatment Outcome
Kidney Failure
Chronic
Female
Hemodialysis
business
Brazil
Kidney disease
Zdroj: Renal failure. 30(2)
ISSN: 1525-6049
Popis: Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic nephropathies, affecting one in every 800-1000 individuals in the worldwide general population and 5-10% of hemodialysis patients. Little data concerning the prevalence of ADPKD in Brazil are available. Thus, the aim of the present study was to investigate both the frequency and clinical profile of ADPKD among hemodialysis patients in south of Brazil.This cross-sectional study consisted of patients from 24 hemodialysis centers. Patients were screened for ADPKD by clinical, laboratorial, and image examination in medical records.Of 1326 patients on hemodialysis in the south of Brazil that composed this study, 99 (7.5%) had polycystic kidney as primary cause for chronic renal failure. Comparisons between ADPKD and non-ADPKD patients revealed no differences regarding mean age, gender, and ethnicity.Our data revealed that ADPKD is prevalent among patients on hemodialysis in the south of Brazil. In addition, the clinical profile of ADPKD is similar to reported data from North America and Europe, putatively due to the similar ethnic composition mainly based on European descents.
Databáze: OpenAIRE
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