Primary Small Cell Neuroendocrine Carcinoma of the Kidney
| Autor: | K G Morgan, Brian P Eyden, Saumitra S Banerjee, R J Barnard |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Enolase Pathology and Forensic Medicine law.invention Mice Cytokeratin Fatal Outcome Structural Biology law medicine Animals Humans Carcinoma Small Cell Kidney biology medicine.disease Immunohistochemistry Kidney Neoplasms Carcinoma Neuroendocrine medicine.anatomical_structure biology.protein Ultrastructure Female Antibody Electron microscope Kidney cancer |
| Zdroj: | Ultrastructural Pathology. 20:141-144 |
| ISSN: | 1521-0758 0191-3123 |
| DOI: | 10.3109/01913129609016308 |
| Popis: | The histological, immunohistochemical, and ultrastructural features of a primary small cell neuroendocrine carcinoma of the renal parenchyma are described. Tumor cells were positive for cytokeratin, neuron-specific enolase, and Leu 7, but Grimelius- and chromogranin-negative. They also exhibited positivity with anti-MIC2 antibody. By electron microscopy, tonofibrils, primitive desmosomes, and dense-core granules with a neuroendocrine appearance were present. This is only the 7th recorded example of such a tumor at this site, which showed an aggressive course characterized by widespread bony metastases. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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