Amyloid Tumor in the Anterior Mediastinum: Report of a Case

Autor: Kanetaka Maeshiro, Mari Fukunaga, Hirohisa Yano, Shinzo Takamori, Kazuo Shirouzu, Akihiro Hayashi, Keisuke Miwa
Rok vydání: 2004
Předmět:
Zdroj: Surgery Today. 34:518-520
ISSN: 1436-2813
0941-1291
Popis: A 33-year-old woman being treated for rheumatoid arthritis was referred to our hospital for investigation of a mediastinal mass. A chest computed tomography scan showed an anterior mediastinal mass, 8.5 x 7.0 cm in size, with a cystic lesion and calcification. These findings were suggestive of either a noninvasive thymoma or a mature teratoma. Therefore, we performed tumor resection and thymectomy. Histologically, the tumor consisted of diffuse deposits of massive eosinophilic amorphous material. The tumor was stained red-orange by Congo red, and the staining disappeared following potassium permanganate digestion. Based on these findings, a diagnosis of reactive amyloidosis of the amyloid A-protein-derived type was made. Amyloidosis in the mediastinum has rarely been described.
Databáze: OpenAIRE