Retinal imaging in Alzheimer's and neurodegenerative diseases

Autor: Heather M. Snyder, Lisa J. Bain, Emily Y. Chew, Peter J. Snyder, Melanie C. W. Campbell, Brett E. Bouma, Brian M. Fernandez, Jessica Alber, Chiara La Morgia, Peter van Wijngaarden, Roxana O. Carare, Michael R. Dueñas, Femke H. Bouwman, Maria C. Carrillo, Delia Cabrera DeBuc, Clemens Alt, M Francesca Cordeiro, Maya Koronyo-Hamaoui, Srinivas R. Sadda
Přispěvatelé: St Marys Development Trust
Rok vydání: 2020
Předmět:
0301 basic medicine
Epidemiology
PROGRESSION
Disease
BLOOD-BASED BIOMARKERS
chemistry.chemical_compound
0302 clinical medicine
early detection
Aged
80 and over
Health Policy
Neurodegeneration
neurodegeneration
Brain
Neurodegenerative Diseases
Alzheimer's disease
Middle Aged
eye
Psychiatry and Mental health
retinal imaging
Retinal imaging
Life Sciences & Biomedicine
Clinical Neurology
Context (language use)
Retina
Article
03 medical and health sciences
Cellular and Molecular Neuroscience
AGE
Developmental Neuroscience
Disease severity
Alzheimer Disease
medicine
Dementia
Humans
Aged
Science & Technology
Modalities
business.industry
1103 Clinical Sciences
Retinal
medicine.disease
DEFINITION
030104 developmental biology
chemistry
Geriatrics
Neurosciences & Neurology
Neurology (clinical)
Geriatrics and Gerontology
1109 Neurosciences
business
Neuroscience
030217 neurology & neurosurgery
Biomarkers
Zdroj: Alzheimers Dement
Snyder, P J, Alber, J, Alt, C, Bain, L J, Bouma, B E, Bouwman, F H, DeBuc, D C, Campbell, M C W, Carrillo, M C, Chew, E Y, Cordeiro, M F, Dueñas, M R, Fernández, B M, Koronyo-Hamaoui, M, la Morgia, C, Carare, R O, Sadda, S R, van Wijngaarden, P & Snyder, H M 2021, ' Retinal imaging in Alzheimer's and neurodegenerative diseases ', Alzheimer's and Dementia, vol. 17, no. 1, pp. 103-111 . https://doi.org/10.1002/alz.12179
ISSN: 1552-5279
DOI: 10.1002/alz.12179
Popis: In the last 20 years, research focused on developing retinal imaging as a source of potential biomarkers for Alzheimer's disease and other neurodegenerative diseases, has increased significantly. The Alzheimer's Association and the Alzheimer's & Dementia: Diagnosis, Assessment, Disease Monitoring editorial team (companion journal to Alzheimer's & Dementia) convened an interdisciplinary discussion in 2019 to identify a path to expedite the development of retinal biomarkers capable of identifying biological changes associated with AD, and for tracking progression of disease severity over time. As different retinal imaging modalities provide different types of structural and/or functional information, the discussion reflected on these modalities and their respective strengths and weaknesses. Discussion further focused on the importance of defining the context of use to help guide the development of retinal biomarkers. Moving from research to context of use, and ultimately to clinical evaluation, this article outlines ongoing retinal imaging research today in Alzheimer's and other brain diseases, including a discussion of future directions for this area of study.
Databáze: OpenAIRE
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