Improvement of the Bioactivity of UHMWPE by Two Different Atmospheric Plasma Treatments

Autor: Jafar Javadpour, Hamid Reza Rezaie, A. Valinataj Omran, Abdessadk Anagri, Farzaneh Arefi-Khonsari, S. Nejatbakhsh, Mujib Ullah, C. Bazin, Massoud Mirshahi, Jerome Pulpytel
Přispěvatelé: Laboratoire Interfaces et Systèmes Electrochimiques (LISE), Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Carcinose Angiogenèse et Recherche Translationnelle, Angiogenese et recherche translationnelle (CART U965), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), School of Metallurgy and Materials Engineering, Iran University of Science and Technology [Tehran] (IUST), Martin, Véronique
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Materials science
Biocompatibility
Surface treatment UHMWPE (ultrahigh molecular weight polyethylene)
General Chemical Engineering
Simulated body fluid
[SDV]Life Sciences [q-bio]
Atmospheric-pressure plasma
Dielectric barrier discharge
engineering.material
01 natural sciences
010305 fluids & plasmas
DBD (dielectrc barrier discharge)
APPJ (atmospheric pressure plasma jet)
Hydroxyapatite (ha)
Coating
0103 physical sciences
[CHIM] Chemical Sciences
[CHIM]Chemical Sciences
010302 applied physics
chemistry.chemical_classification
[CHIM.MATE] Chemical Sciences/Material chemistry
General Chemistry
Polymer
Adhesion
[CHIM.MATE]Chemical Sciences/Material chemistry
Simulated body fluid (SBF)
Condensed Matter Physics
Surfaces
Coatings and Films
[SDV] Life Sciences [q-bio]
chemistry
Chemical engineering
engineering
Surface modification
Zdroj: Plasma Chemistry and Plasma Processing
Plasma Chemistry and Plasma Processing, Springer Verlag, 2021, 41 (41), pp.245-264. ⟨10.1007/s11090-020-10134-7⟩
Plasma Chemistry and Plasma Processing, 2021, 41 (41), pp.245-264. ⟨10.1007/s11090-020-10134-7⟩
ISSN: 0272-4324
1572-8986
Popis: "The final publication is available at link.springer.com"; International audience; In this research work we demonstrated that a helium/oxygen Dielectric Barrier Discharge conferred hydrophilic functional groups onto the surface, which lead to enhanced bioactivity of UHMWPE without affecting the biocompatibility of the polymer. The latter was checked by increased adhesion of fibroblast cells to the polymer. The effects of the He/2% O2 DBD plasma was compared for the first time to a rotating blown arc atmospheric pressure plasma jet (r-APPJ) in air. The results show a better functionalization as well as stability of the surface properties of the films treated with the DBD. The surface modified UHMWPE once immersed in a Simulated Body Fluid induced the formation of nucleus of hydroxyapatite (calcium phosphate) leading to the growth of a thick apatite coating which was followed up to 14 days, which can be expected to be highly bioactive. Surface characterization techniques also showed different chemical moieties in the case of the two different atmospheric discharges. DBD discharge in He/2% O2, leading to more stable polar functions grafted to a crosslinked polymer surface, proved to be more bioactive than UHMWPE treated by a r-APPJ in air. The latter treatment lead to grafting of less oxygen containing groups to the surface as well as to LMWOM created on r-APPJ treated UHMWPE which are unstable in aqueous media used both in SBF and fibroblasts in DMEM.
Databáze: OpenAIRE
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