The effects of ochratoxin/aluminosilicate interaction on the tissues and humoral immune response of broilers
| Autor: | A. Maiorka, Elizabeth Santin, Everton L. Krabbe, Antonio Carlos Alessi, Paulo César Maiorka, Antonio Carlos Paulillo |
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| Rok vydání: | 2002 |
| Předmět: |
Male
medicine.medical_specialty animal structures Newcastle disease virus Cell Count Kidney medicine.disease_cause Newcastle disease chemistry.chemical_compound Bursa of Fabricius Immune system Food Animals Internal medicine medicine Animals Drug Interactions Ochratoxin Poultry Diseases General Immunology and Microbiology biology Toxin Glomerular basement membrane food and beverages Viral Vaccines Histology Organ Size Hyperplasia biology.organism_classification medicine.disease Ochratoxins Endocrinology medicine.anatomical_structure Liver chemistry Immunology Aluminum Silicates Female Animal Science and Zoology Chickens |
| Zdroj: | Avian Pathology. 31:73-79 |
| ISSN: | 1465-3338 0307-9457 |
| DOI: | 10.1080/03079450120106642 |
| Popis: | This study aimed to evaluate the effect of dietary ochratoxin, in the presence or absence of aluminosilicate, on the histology of the bursa of Fabricius, liver and kidneys, and on the humoral immune response of broilers vaccinated against Newcastle disease virus. The exposure of birds to 2 p.p.m. ochratoxin, in the presence or absence of aluminosilicate, reduced their humoral immune response and the number of mitotic cells in the bursa. The relative weight of the livers of the birds exposed to this toxin was increased and, microscopically, there was hepatocyte vacuolation and megalocytosis with accompanying hyperplasia of the biliary epithelium. The kidneys showed hypertrophy of the renal proximal tubular epithelium, with thickening of the glomerular basement membrane. Aluminosilicate did not ameliorate the deleterious effects of the ochratoxin. |
| Databáze: | OpenAIRE |
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