Fentanyl-Induced Respiratory Depression: A Narrative Review on the Possible Single-Nucleotide Polymorphism
| Autor: | Srisruthi Udayakumar, Prabha Udayakumar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
business.industry
Pain medicine Single-nucleotide polymorphism Review Article Bioinformatics Fentanyl respiratory depression Anesthesia single-nucleotide polymorphisms Materials Chemistry Medicine Narrative review Clinical efficacy Respiratory system business Pharmacogenetics Depression (differential diagnoses) medicine.drug pharmacogenetics |
| Zdroj: | Anesthesia, Essays and Researches |
| ISSN: | 2229-7685 0259-1162 |
| Popis: | Opioid-related respiratory depression is a serious clinical problem as it can cause multiple deaths and anoxic brain injury. Genetic variations influence the safety and clinical efficacy of fentanyl. Pharmacogenetic studies help in identifying single-nucleotide polymorphisms (SNPs) associated with fentanyl causing respiratory depression and aid clinician in personalized pain medicine. This narrative review gives an insight of the common SNPs associated with fentanyl. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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