Oral consumption of potential probiotic Saccharomyces boulardii strain Unique 28 in patients with acute diarrhoea: a clinical report
| Autor: | S. Bhonagiri, M. Ratna Sudha, M. Asin Kumar |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Microbiology (medical)
Adult Diarrhea Male Abdominal pain medicine.medical_specialty Drug-Related Side Effects and Adverse Reactions Administration Oral Physical examination Microbiology chemistry.chemical_compound Saccharomyces Internal medicine medicine Humans Adverse effect Creatinine medicine.diagnostic_test biology business.industry Incidence (epidemiology) Probiotics Complete blood count biology.organism_classification Surgery Diet Blood pressure Treatment Outcome chemistry Female medicine.symptom business Saccharomyces boulardii |
| Zdroj: | Beneficial microbes. 3(2) |
| ISSN: | 1876-2891 |
| Popis: | This study was conducted to evaluate the efficacy and safety of Saccharomyces boulardii strain Unique 28 in patients suffering from acute diarrhoea. A total of 25 patients (average age 30.72±4.38 years) with symptoms of acute diarrhoea (≥3 loose motion in last 24 hours for 9 cfu/capsule) twice a day for a duration of 10 days. Primary outcome measures such as duration of diarrhoea, frequency of defaecation, abdominal pain and consistency of stool were analysed on day 1, 3, 6 and 10 of the study. Secondary outcome measures were evaluated by assessment of incidence and type of adverse events (blood pressure and pulse rate), physical examination and clinical laboratory tests (complete blood count, glutamic-pyruvic transaminase, serum creatinine, stool examination and microscopy and these tests were performed on day 1 and 10 of the study. The results of the present study indicate that the mean duration of diarrhoea decreased from 34.20±4.25 to 9.40±3.00 (P |
| Databáze: | OpenAIRE |
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