Pediatric Conjunctivitis and Air Pollution Exposure: A Prospective Observational Study
| Autor: | Pia Allegri, Marika Dello Strologo, Paolo Nucci, Francesco Pichi, Massimiliano Serafino, Matteo Sacchi, Stefano De Cillà, Edoardo Villani |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Time Factors Adolescent Air pollution exposure Air pollution 010501 environmental sciences medicine.disease_cause 01 natural sciences 03 medical and health sciences 0302 clinical medicine Air Pollution Prevalence medicine Humans Prospective Studies Child 0105 earth and related environmental sciences business.industry Incidence Infant General Medicine Conjunctivitis Ophthalmology Italy Child Preschool 030221 ophthalmology & optometry Etiology Female Particulate Matter Observational study business Ocular surface Follow-Up Studies |
| Zdroj: | Seminars in Ophthalmology. 32:407-411 |
| ISSN: | 1744-5205 0882-0538 |
| DOI: | 10.3109/08820538.2015.1115088 |
| Popis: | To investigate, in pediatric patients, the rate and clinical features of unspecific conjunctivitis of unknown origin (UCUO) and to evaluate their relationship with air pollution.From January to December 2013, we consecutively screened all of the patients referred for symptomatic ocular surface inflammation. Inclusion criteria for this study were age14, diagnosis of conjunctivitis, residence in the Lombardia region. UCUO was defined as conjunctivitis of unknown etiology, not clearly due to infection or allergy. Based on addresses of residence and sites of 73 automatic air pollution monitoring stations (locations and mean annual particulate matter (PM) 10 and 2.5 concentrations were provided by the Regional Environmental Protection Agency (ARPA) Lombardia), each patient was paired with a value of exposure to PM. Relationship between UCUO and PM exposure was investigated.A total of 132 of 251 screened children were included in this study. UCUO was diagnosed in 48/132 patients. The most common symptoms and signs in UCUO children were foreign body sensation (37/48) and conjunctival hyperemia (45/48), respectively. PM10 exposure value was significantly higher in UCUO (33.5±5.4µg/m3) compared to other groups (P0.001, ANOVA). UCUO/total conjunctivitis ratio was significantly higher in residents in areas with more than 75 (Q3) days/year exceeding 50µg/m3 (EU legal limit) compared to areas with less than 45 (Q1) exceedances/year: 24/39: 61% vs 8/35: 23%; P0.001, Chi-square test.Our data suggest a relationship between UCUO and air pollution. This form of conjunctivitis is not rare in pediatric patients and may be the most frequent in most polluted areas. |
| Databáze: | OpenAIRE |
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