Diagnosis of acute hepatitis E infection utilizing enzyme immunoassay
| Autor: | Thomas J. Layden, George J. Dawson, David Pitrak, Daniel C. Shin, Lino J. DeGuzman, Timothy J. Holzer |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Male medicine.medical_specialty Physiology viruses medicine.disease_cause Epitope Immunoenzyme Techniques Hepatitis E virus Internal medicine medicine Humans Hepatitis Antibodies Hepatitis biology medicine.diagnostic_test business.industry Gastroenterology virus diseases Hepatology medicine.disease Virology digestive system diseases Hepatitis E Immunoglobulin M Immunoglobulin G Immunoassay Acute Disease Immunology biology.protein Viral disease Antibody business Viral hepatitis |
| Zdroj: | Digestive Diseases and Sciences. 39:1691-1693 |
| ISSN: | 1573-2568 0163-2116 |
| DOI: | 10.1007/bf02087777 |
| Popis: | Acute hepatitis E infection was diagnosed in a Pakistani immigrant admitted to the University of Illinois Hospital. Utilizing enzyme immunoassay (EIA) tests, specific IgG and IgM class antibodies to three different epitopes of hepatitis E virus (HEV) were detected 12 weeks after the onset of illness and in the early convalescent stage. Sixteen months after the onset of hepatitis, IgM anti-HEV was no longer detectable. Low levels of IgG class anti-HEV antibodies continued to be detected. We demonstrate the utility of the EIA HEV assay to diagnose prospectively acute HEV infection. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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