Blood Pressure Coefficient of Variation and Its Association With Cardiac Surgical Outcomes
| Autor: | Varesh Prasad, Balachundhar Subramaniam, Victor Novack, Ariel Mueller, Thomas Heldt, Sayuri P. Jinadasa, Kathirvel Subramaniam |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Databases Factual Risk Assessment law.invention 03 medical and health sciences 0302 clinical medicine 030202 anesthesiology law Risk Factors Internal medicine Cardiopulmonary bypass medicine Humans Arterial Pressure Hospital Mortality Renal Insufficiency Cardiac Surgical Procedures Perioperative Period Aged Retrospective Studies Cardiopulmonary Bypass business.industry Retrospective cohort study Odds ratio Perioperative Middle Aged Confidence interval Cardiac surgery Anesthesiology and Pain Medicine Blood pressure Treatment Outcome Cardiothoracic surgery Cardiology Female business 030217 neurology & neurosurgery |
| Zdroj: | Anesthesia and analgesia. 127(4) |
| ISSN: | 1526-7598 |
| Popis: | BACKGROUND Multiple studies completed in the ambulatory nonsurgical setting show a significant association between short- and long-term blood pressure variability and poor outcomes. However, perioperative blood pressure variability outcomes have not been well studied, especially in the cardiac surgical setting. In this study, we sought to assess whether systolic and mean arterial blood pressure variability were associated with 30-day mortality and in-hospital renal failure in patients undergoing cardiac surgery requiring cardiopulmonary bypass. Furthermore, blood pressure variability has not been evaluated specifically during each phase of surgery, namely in the pre-, intra- and postbypass phases; thus, we aimed also to assess whether outcomes were associated with phase-specific systolic and mean arterial blood pressure variability. METHODS All patients undergoing cardiac surgery from January 2008 to June 2014 were enrolled in this retrospective, single-center study. Demographic, intraoperative, and postoperative outcome data were obtained from the institution's Society of Thoracic Surgery database and Anesthesia Information Management System. Systolic and mean arterial blood pressure variability were assessed using the coefficient of variation (CV). The primary outcomes were 30-day mortality and in-hospital renal failure in relation to the entire duration of a case, while the secondary outcomes assessed phase-specific surgical periods. In an effort to control the family-wise error rate, P values |
| Databáze: | OpenAIRE |
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