Static magnetic field stimulation applied over the cervical spinal cord can decrease corticospinal excitability in finger muscle
| Autor: | Kimitaka Nakazawa, Kento Nakagawa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
medicine.medical_treatment Stimulation Electromyography lcsh:RC321-571 tSMS transcranial static magnetic stimulation 03 medical and health sciences FDI first dorsal interosseous 0302 clinical medicine Physiology (medical) tsSMS transspinal static magnetic stimulation Medicine Motor evoked potential lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Static magnetic field M1 primary motor cortex Spinal cord medicine.diagnostic_test business.industry Neuromodulation TMS transcranial magnetic stimulation Sham Intervention equipment and supplies Neuromodulation (medicine) Transcranial magnetic stimulation 030104 developmental biology medicine.anatomical_structure Neurology MEP motor evoked potential Clinical and Research Article Corticospinal tract Neurology (clinical) Primary motor cortex business Neuroscience human activities EMG electromyography 030217 neurology & neurosurgery |
| Zdroj: | Clinical Neurophysiology Practice Clinical Neurophysiology Practice, Vol 3, Iss, Pp 49-53 (2018) |
| ISSN: | 2467-981X |
| Popis: | Highlights • Static magnetic field stimulation was delivered on cervical spinal cord. • Trans-spinal static magnetic field stimulation (tsSMS) decreased MEP amplitudes. • The suppressive effect of tsSMS was not maintained after the intervention ceased. Objective Transcranial static magnetic field stimulation has recently been demonstrated to modulate cortical excitability. In the present study, we investigated the effect of transspinal static magnetic field stimulation (tsSMS) on excitability of the corticospinal tract. Methods A compact magnet for tsSMS (0.45 Tesla) or a stainless steel cylinder for sham stimulation was positioned over the neck (C8 level) of 24 able-bodied subjects for 15 min. Using 120% of the resting motor threshold transcranial magnetic stimulation intensity, motor evoked potentials (MEPs) were measured from the first digital interosseous muscle before, during, and after the tsSMS or sham intervention. Results Compared with baseline MEP amplitudes were decreased during tsSMS, but not during sham stimulation. Additionally, during the intervention, MEP amplitudes were lower with tsSMS than sham stimulation, although these effects did not last after the intervention ceased. Conclusions The results suggest that static magnetic field stimulation of the spinal cord by a compact magnet can reduce the excitability of the corticospinal tract. Significance Transspinal static magnetic field stimulation may be a new non-invasive neuromodulatory tool for spinal cord stimulation. Its suppressive effect may be applied to patients who have pathological hyperexcitability of the spinal neural network. |
| Databáze: | OpenAIRE |
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