Establishing the Role of Angiotensin-Converting Enzyme in Renal Function and Blood Pressure Control through the Analysis of Genetically Modified Mice

Autor:	Kristen Frenzel, Jon W. Adams, Kenneth E. Bernstein, Ping Li, Xiao Z. Shen, Justin M. Cole, Sebastien Fuchs, Hong D. Xiao
Rok vydání:	2005
Předmět:	medicine.medical_specialty Hypertension Renal Blood Pressure Peptide Peptidyl-Dipeptidase A Kidney Mice Internal medicine Renin–angiotensin system Animals Medicine Mice Knockout chemistry.chemical_classification Angiotensin II receptor type 1 biology business.industry Reabsorption Angiotensin-converting enzyme General Medicine Angiotensin II Disease Models Animal Endocrinology Blood pressure chemistry Nephrology Knockout mouse cardiovascular system biology.protein business circulatory and respiratory physiology
Zdroj:	Journal of the American Society of Nephrology. 16:583-591
ISSN:	1046-6673
DOI:	10.1681/asn.2004080693
Popis:	Angiotensin II is a vasoconstrictor and a hypertensive peptide that binds to the AT1 receptor and, through both direct and indirect mechanisms, induces salt reabsorption. Also, angiotensin II is thought to be a profibrotic and proproliferative peptide; abundant evidence now suggests that angiotensin
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f1196c3f4d3e132f3039bf43b3898b https://doi.org/10.1681/asn.2004080693 Zobrazit plný text záznamu