Effects in the liver of methylene chloride inhaled alone and with ethyl alcohol
| Autor: | Marilyn F. Balmer, Frank A. Smith, C. L. Yuile, L. J. Leach |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Male
Time Factors Guinea Pigs Environment controlled Alcohol Pharmacology Models Biological Chloride chemistry.chemical_compound Hepatic damage Hydrocarbons Chlorinated medicine Animals Organic chemistry Methylene Methylene Chloride Ethanol Dose-Response Relationship Drug Inhalation Public Health Environmental and Occupational Health Drug Synergism Environment Controlled Liver chemistry Antagonism medicine.drug |
| Zdroj: | American Industrial Hygiene Association Journal. 37:345-352 |
| ISSN: | 0002-8894 |
| DOI: | 10.1080/0002889768507469 |
| Popis: | When high concentrations of methylene chloride in combination with high concentrations of ethanol were inhaled for one day by guinea pigs, the extent of the hepatic damage induced suggested an antagonism between the effects of the two agents. However, exposure for five days to approximately 500 ppm of methylene chloride plus high concentrations of ethanol suggested ethanol may potentiate the effects of methylene chloride. |
| Databáze: | OpenAIRE |
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