Using high density EEG to assess TMS treatment in patients with schizophrenia
| Autor: | Eysteinn Ívarsson, Paolo Gargiulo, Elena Pegolo, Ovidiu C. Banea, Sara Marcu, Romain Aubonnet, Viktor D Jónasson, Aron D. Jónasson |
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| Přispěvatelé: | Verkfræðideild (HR), Department of Engineering (RU), Tæknisvið (HR), School of Technology (RU), Háskólinn í Reykjavík, Reykjavik University |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Heilarit Brain electrical activity high density EEG medicine.medical_treatment lcsh:Medicine Audiology Stimulus (physiology) Electroencephalography Article lcsh:QM1-695 03 medical and health sciences 0302 clinical medicine Geðklofi Medicine Orthopedics and Sports Medicine In patient P300 Molecular Biology Sensory gating medicine.diagnostic_test High density EEG Heilastarfsemi business.industry lcsh:R P50 lcsh:Human anatomy Cell Biology High density eeg Auditory evoked responses 030227 psychiatry schizophrenia Transcranial magnetic stimulation medicine.anatomical_structure Schizophrenia Neurology (clinical) business Biomedical engineering 030217 neurology & neurosurgery |
| Zdroj: | European Journal of Translational Myology European Journal of Translational Myology (2020) Scopus-Elsevier |
| ISSN: | 2037-7460 2037-7452 |
| DOI: | 10.4081/ejtm.2019.8903 |
| Popis: | Publisher's version (útgefin grein) We present preliminary results from the ongoing study entitled "Icelandic AVH-TMS" which aim is to study the effectiveness of repetitive transcranial magnetic stimulation (rTMS) treatment for patients with schizophrenia and with persistent auditory verbal hallucinations (AVH) using symptoms and psychometric scales and high-density EEG system (256 channels). The aim of the present work was to describe cortical topography of the auditory evoked responses like P50 and N100-P300 complex in healthy participants and patients with schizophrenia and to define a robust methodology of signal quantification using dense-array EEG. Preliminary data is shown for three healthy participants and three patients in baseline conditions and for two patients we show the results recorded before and after 10 days rTMS treatment. Our results show differences in sensory gating (P50 suppresion) and a stronger N100-P300 response to rare audio stimulus after the treatment. Moreover we show the value of assessing brain electrical activity from high-density EEG (256 channels) analyzing the results in different regions of interest. However, it is premature and hazardous to assume that rTMS treatment effectiveness in patients with AVH can be assessed using P50 suppression ratio. "Peer Reviewed" |
| Databáze: | OpenAIRE |
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