Bioactive 4-hydroxycinnamide and bioactivities of Polyalthia cerasoides

Autor: Treeratanapiboon, L., Worachartcheewan, A., Suksrichavalit, T., Kiatfuengfoo, R., Prachayasittikul, S., Ruchirawat, S., Virapong Prachayasittikul
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Scopus-Elsevier
EXCLI Journal
DOI: 10.17877/de290r-1115
Popis: Constituents from Polyalthia cerasoides, stem bark methanol extract, were previously documented. This study reports the first isolation of bioactive N-(4-hydroxy-β-phenethyl)-4-hydroxycinnamide (1) from ethyl acetate extract of the plant species including stigmasterol and a mixture of triterpenes from hexane and dichloromethane extracts. Trace essential elements were found in the hexane extract in ppm level. The plant extracts were evaluated for their antimicrobial and antioxidative activities. The dichloromethane extract displayed the highest activity against Corynebacterium diphtheriae NCTC 10356 with MIC of 32 μg/mL, as well as, the highest SOD activity with an IC50 of 4.51 μg/mL.
EXCLI Journal ; Vol. 10, 2011
Databáze: OpenAIRE