Instrumental evaluation of anti-aging effects of cosmetic formulations containing palmitoyl peptides, Silybum marianum seed oil, vitamin E and other functional ingredients on aged human skin
| Autor: | Ji Hyun Kim, Ho Jung Jung, Hyung Jin Hahn, Seung Bin Kwon, Med Christine Schrammek-Drusios, Sungkwan An, Sung Nae Lee, In-Sook An, Kyu Joong Ahn |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Cancer Research medicine.medical_specialty Erythema media_common.quotation_subject medicine.medical_treatment SILYBUM MARIANUM SEED OIL Human skin Skin tone Cosmetics Silybum marianum Skin Aging 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Immunology and Microbiology (miscellaneous) medicine media_common integumentary system biology business.industry Vitamin E Articles General Medicine biology.organism_classification Dermatology 030104 developmental biology medicine.symptom business |
| Zdroj: | Experimental and Therapeutic Medicine. 12:1171-1176 |
| ISSN: | 1792-1015 1792-0981 |
| DOI: | 10.3892/etm.2016.3447 |
| Popis: | Anti-aging cosmetics are widely used for improving signs of aged skin such as skin wrinkles, decreased elasticity, low dermal density and yellow skin tone. The present study evaluated the effects of cosmetic formulations, eye cream and facial cream, containing palmitoyl peptides, Silybum marianum (S. marianum) seed oil, vitamin E and other functional ingredients on the improvement of facial wrinkles, elasticity, dermal density and skin tone after 4 weeks period of application on aged human skin. Healthy volunteers (n=20) with aged skin were recruited to apply the test materials facially twice per day for 4 weeks. Skin wrinkles, elasticity, dermal density and skin tone were measured instrumentally for assessing the improvement of skin aging. All the measurements were conducted prior to the application of test materials and at 2 and 4 weeks of treatment. Crow's feet wrinkles were decreased 5.97% after 2 weeks of test material application and 14.07% after 4 weeks of application in comparison of pre-application. Skin elasticity was increased 6.81% after 2 weeks and 8.79% after 4 weeks. Dermal density was increased 16.74% after 2 weeks and 27.63% after 4 weeks. With the L* value indicating skin brightness and the a* value indicating erythema (redness), the results showed that brightness was increased 1.70% after 2 weeks and 2.14% after 4 weeks, and erythema was decreased 10.45% after 2 weeks and 22.39% after 4 weeks. Hence, the test materials appear to exert some degree of anti-aging effects on aged human skin. There were no abnormal skin responses from the participants during the trial period. We conclude that the facial and eye cream containing palmitoyl peptides and S. marianum seed oil, vitamin E and other ingredients have effects on the improvement of facial wrinkles, elasticity, dermal density and skin tone. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|