LC-MS Analysis and Antioxidant Activity of the Hydro-alcoholic Extract of Melissa Officinalis L. From Algeria
| Autor: | Hichem Mohammedi, Imad Mennai, Chawki Bensouici, Salim Gasmi, Brahim Ben Aicha, Rachid Rouabhi |
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| Rok vydání: | 2020 |
| Předmět: |
hydro-methanolic extract
Antioxidant Traditional medicine Chemistry Process Chemistry and Technology medicine.medical_treatment 010401 analytical chemistry antioxidant activity General. Including alchemy 04 agricultural and veterinary sciences General Chemistry lc-ms analysis 040401 food science 01 natural sciences 0104 chemical sciences QD1-65 0404 agricultural biotechnology Liquid chromatography–mass spectrometry medicine Environmental Chemistry Melissa officinalis QD1-999 melissa officinalis l |
| Zdroj: | Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, Vol 15, Iss 2, Pp 78-87 (2020) |
| ISSN: | 2345-1688 1857-1727 |
| Popis: | The present work focuses on evaluation of the chemical composition and antioxidant activity of the hydro-methanolic extract of Melissa officinalis from Algeria. The liquid chromatography-mass spectrometry analysis allowed the identification of six compounds: caffeic acid, caftaric acid, hydroxyjasmonic acid glucoside, caftaric acid glucoside, rosmarinic acid and sagerinic acid. The in-vitro antioxidant activity of the hydro-methanolic extract was evaluated by using four different methods including: radical scavenging assay (DPPH), scavenging activity (ABTS), cupric reducing antioxidant capacity, and ferric reducing power assay. The extract exhibited a relatively strong antioxidant activity compared to the synthetic antioxidants. The highest radical scavenging activity was registered using DPPH and ABTS methods, IC50= 20.53±2.64 μg/mL and 22.50±0.67 μg/mL, respectively. These results suggest that Melissa officinalis L. could be considered a potential source of natural antioxidants with potential interest in the agrochemical and pharmaceutical industries. |
| Databáze: | OpenAIRE |
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