The invention and development of enflurane, isoflurane, sevoflurane, and desflurane
| Autor: | Ross C. Terrell, David S. Warner |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
inorganic chemicals
Methyl Ethers Hydrocarbons Fluorinated Isoflurane business.industry Chemistry Pharmaceutical Volatile anesthetic Enflurane Desflurano Medicinal chemistry Sevoflurane Desflurane Anesthesiology and Pain Medicine Anesthesia Drug Design Anesthetic medicine Animals Humans business medicine.drug |
| Zdroj: | Anesthesiology. 108(3) |
| ISSN: | 1528-1175 |
| Popis: | Thirty-six halogenated Me Et ethers have been synthesized for evaluation as volatile anesthetics. Eleven of the ethers were too unstable to test, and, of the remaining 25, 13 had promising anesthetic properties in mice and are suitable for study in larger animals. Those ethers having one H with at least 2 halogens other than F or 2 or more H with at least one Br or Cl were the best anesthetics. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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