(S)-(−)-4-[4-[2-(Isochroman-1-yl)ethyl]piperazin-1-yl]benzenesulfonamide, a Selective Dopamine D4 Antagonist
Autor: | J. N. Duncan, M. W. Smith, Rita M. Huff, Robert A. Lahti, Lawson Cf, Schlachter Sk, Tenbrink Ruth E, Douglas W. Harris, I. J. Martin, B. S. Lutzke, John C. Sih, Rees Sa, C. L. Bergh |
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Rok vydání: | 1996 |
Předmět: |
Quinpirole
Stereochemistry Biological Availability CHO Cells Chemical synthesis Piperazines Dopamine Cricetinae Drug Discovery medicine Animals Humans Ergolines chemistry.chemical_classification Sulfonamides Molecular Structure Bicyclic molecule Chemistry Receptors Dopamine D4 Antagonist Biological activity Receptors Adrenergic Sulfonamide Dopamine D2 Receptor Antagonists Dopamine receptor Receptors Serotonin Dopamine Agonists Schizophrenia Dopamine Antagonists Molecular Medicine Enantiomer Antipsychotic Agents Protein Binding medicine.drug |
Zdroj: | Journal of Medicinal Chemistry. 39:2435-2437 |
ISSN: | 1520-4804 0022-2623 |
DOI: | 10.1021/jm960084f |
Databáze: | OpenAIRE |
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