Sesquiterpene Glucosides from Anti-leukotriene B4Release Fraction ofTaraxacum Officinale

Autor:	Yoshiki Kashiwada, Shigeo Tanaka, Harumi Tsukada, T. Taga, Koichiro Takanaka, Yoshihisa Miwa, Yasumasa Ikeshiro
Rok vydání:	2001
Předmět:	Anti-HIV Agents Neutrophils Leukotriene B4 Stereochemistry Molecular Conformation Pharmaceutical Science Fraction (chemistry) Asteraceae Crystallography X-Ray Sesquiterpene Plant Roots Analytical Chemistry Structure-Activity Relationship chemistry.chemical_compound Glucosides Japan Taraxacum officinale Drug Discovery Humans Nuclear Magnetic Resonance Biomolecular Calcimycin Cells Cultured Chromatography High Pressure Liquid Inflammation Pharmacology Plants Medicinal Dose-Response Relationship Drug Molecular Structure Plant Extracts Organic Chemistry Stereoisomerism General Medicine Complementary and alternative medicine Biochemistry chemistry HIV-1 Molecular Medicine Chromatography Thin Layer Sesquiterpenes HeLa Cells
Zdroj:	Journal of Asian Natural Products Research. 3:191-197
ISSN:	1477-2213 1028-6020
DOI:	10.1080/10286020108041390
Popis:	Chemical examination of the MeOH extract of the root of Taraxacum officinale, which exhibited inhibitory activity on the formation of leukotriene B4 from activated human neutrophils, has resulted in the isolation of 14-O-β-D-glucosyl-11,13-dihydro-taraxinic acid (1) and 14-O-β-D-glucosyl-taraxinic acid (2). The absolute stereostructure of 1 has been established by X-ray chrystallographic examination.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d93fbfb414f27d6284a3f07ef5ca16 https://doi.org/10.1080/10286020108041390 Zobrazit plný text záznamu