Gas chromatographic-mass spectrometric study of lipids and rapid diagnosis of Mycobacterium tuberculosis
| Autor: | S.A. Plyusnin, M.G. Kovaleva, E.E. Kuznetsova, T.I. Mayakova |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Tuberculosis
Microbiological culture Tuberculostearic acid Sensitivity and Specificity Gas Chromatography-Mass Spectrometry Mycobacterium tuberculosis chemistry.chemical_compound medicine Humans Tuberculosis Pulmonary Chromatography Lung biology Respiratory disease Sputum General Chemistry biology.organism_classification medicine.disease medicine.anatomical_structure chemistry Gas chromatography–mass spectrometry medicine.symptom Biomarkers Stearic Acids |
| Zdroj: | Journal of Chromatography B: Biomedical Sciences and Applications. 672:133-137 |
| ISSN: | 0378-4347 |
| DOI: | 10.1016/0378-4347(95)00192-l |
| Popis: | The method suggested is based on the identification of tuberculostearic acid as a Mycobacterium tuberculosis marker. Bacterial culture and sputum of patients with pulmonary tuberculosis and lung diseases of non-tuberculous etiology were investigated. A complete coincidence of the results of bacteriological and gas chromatographic-mass spectrometric (GC-MS) methods used in examining a group of patients with pulmonary tuberculosis was found. GC-MS ion monitoring provides a highly sensitive and rapid technique for the diagnosis of pulmonary tuberculosis. |
| Databáze: | OpenAIRE |
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