Evolution of Helicobacter pylori associated with gastroduodenal ulcers or erosions in children over the past 23 years: Decline or steady state?

Autor:	Marie Burgard, Jean Vanderpas, Carine De Prez, Veronique Yvette Miendje-Deyi, Patrick Bontems, Joyce Mekhael, Kallirroi Kotilea, Samy Cadranel
Rok vydání:	2019
Předmět:	Male medicine.medical_specialty Helicobacter pylori infection Peptic Ulcer Adolescent Biopsy Gastroenterology Helicobacter Infections 03 medical and health sciences 0302 clinical medicine children Internal medicine Duodenal erosions medicine Prevalence Gastro-entérologie Upper gastrointestinal Humans Endoscopy Digestive System Pathologie maladies infectieuses Child Retrospective Studies peptic ulcer disease medicine.diagnostic_test biology Helicobacter pylori business.industry Histocytochemistry Incidence Infant Histology General Medicine Sciences bio-médicales et agricoles biology.organism_classification Upper gastrointestinal endoscopy Endoscopy Infectious Diseases 030220 oncology & carcinogenesis Child Preschool 030211 gastroenterology & hepatology Female business Pediatric population
Zdroj:	Helicobacter, 24 (5
ISSN:	1523-5378
Popis:	Background: Recent data suggest that in children, the proportion of gastroduodenal ulcers/erosions associated with Helicobacter pylori infection is currently lower than expected. In this study, we trace this proportion over two decades. Methods: We reviewed the reports of all upper gastrointestinal endoscopies with biopsies for histology and culture over the past 23 years. H pylori status was assessed using several invasive methods. The infection rate during different time periods was compared between children with lesions and controls. Results: A total of 7849 endoscopies were performed in 5983 children (2874 F/3109 M, median age 7.6 years, range 0.1-17.9 years). The endoscopy report was missing in 316 patients. At the first upper gastrointestinal endoscopy, 12.1% of the children presented with gastric and/or duodenal ulcers or erosions with an H pylori infection rate of 35.4%, whereas no such lesions were observed in 87.9% of children in whom the H pylori infection rate was 21.3%. The risk factors associated with such lesions were older age (P SCOPUS: ar.j info:eu-repo/semantics/published
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d72a41abfb7016c2205fc07ffa5639 https://pubmed.ncbi.nlm.nih.gov/31282120 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.