Macrophage Inflammatory Protein-1 Alpha: A Paradox?

Autor: Anne N. Parker, Ian B. Pragnell
Rok vydání: 2016
Předmět:
Zdroj: Hematology (Amsterdam, Netherlands). 2(4)
ISSN: 1024-5332
Popis: Macrophage inflammatory protein - 1 alpha (MIP-1α) is an 8kD protein which tends to form aggregates and is a member of the C-X-C chemokine subfamily, being a pro-inflammatory agent and is chemotactic for lymphocytes. MIP-1α has been shown to inhibit haemopoietic progenitor cell proliferation in vivo and in vitro and to reduce haemopoietic stem cell loss with improved neutrophil recovery after radiotherapy or chemotherapeutic agents in vivo.
Databáze: OpenAIRE