Phosphorus counting table for the control of serum phosphorus levels without phosphate binders in hemodialysis patients
| Autor: | Vivianne Rêis Bertonsello-Catto, Leandro Junior Lucca, José Abrão Cardeal da Costa |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty medicine.drug_class Endocrinology Diabetes and Metabolism medicine.medical_treatment Parathyroid hormone chemistry.chemical_element 030209 endocrinology & metabolism Young Adult 03 medical and health sciences Hyperphosphatemia chemistry.chemical_compound 0302 clinical medicine Renal Dialysis Surveys and Questionnaires Internal medicine EDUCAÇÃO ALIMENTAR E NUTRICIONAL medicine Humans Aged Aged 80 and over 030109 nutrition & dietetics Nutrition and Dietetics business.industry Phosphorus Middle Aged medicine.disease Phosphate Phosphate binder Clinical trial chemistry Kidney Failure Chronic Patient Compliance Female Hemodialysis business Kidney disease |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| Popis: | Summary Background and aims Hyperphosphatemia constitutes one of the major problems faced by patients with chronic kidney disease, and nourishment plays a significant role in its control. The present study aimed to evaluate the maintenance of phosphorus serum levels by observing measurements before and after an intervention using the Phosphorus Counting Table (PCT), in hemodialysis patients lacking phosphate binder use. Methods The assessment included fifty individuals on hemodialysis who underwent phosphate binder suspension 30 days prior to the intervention. The participants received food and nutrition education on the PCT tool, which assists in the control of dietary phosphorus intake, and followed its instructions for two months. Fasting blood samples were collected at three moments for phosphorus, total calcium, and parathyroid hormone (PTH) analysis. The study sample was initially analyzed as a whole, then sub-classified into two groups: adherence and non-adherence. Results At the end of the study, no significant difference in serum phosphorus was observed in the total and the adherence groups (p > 0.05). The non-adherence group showed a substantial increase of 0.74 mg/dL in serum phosphorus levels and 6.16 mg2/dL2 in the calcium-phosphorus product after the intervention. Meanwhile, the calcium-phosphorus product improved from 56.42 ± 11.49 mg2/dL2 to 51.05 ± 10.67 mg2/dL2 in the adherence group. Serum calcium levels did not change throughout the study in the three groups. A significant increment in PTH serum levels was observed at the end of the study in all groups. Conclusion The PCT showed to be efficient in the maintenance of serum phosphorus in the individuals who adhered well to the tool, without the administration of phosphate binders. Such a method can assist in patient adherence to treatment and enables better diet flexibility. The present trial was registered under the Brazilian Clinical Trials Registry (Rebec). Registration number: RBR-2vzd48. |
| Databáze: | OpenAIRE |
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