Target-Induced Aggregation of Gold Nanoparticles for Colorimetric Detection of Bisphenol A
| Autor: | Sehan Jeong, Min Geun Jo, Woo Young Kwon, Hyung Joo Choi, Ki Soo Park, Miran Lee, Seokjoon Kim, Hyunmin Eun, Yong Hwan Kim, Sung Hyun Hwang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Tolerable daily intake
Bisphenol A endocrine system Chromatography Materials science Article Subject urogenital system Aptamer 010401 analytical chemistry Heat resistance 02 engineering and technology 021001 nanoscience & nanotechnology 01 natural sciences Rapid detection 0104 chemical sciences chemistry.chemical_compound Tap water chemistry Colloidal gold lcsh:Technology (General) lcsh:T1-995 General Materials Science Naked eye 0210 nano-technology hormones hormone substitutes and hormone antagonists |
| Zdroj: | Journal of Nanomaterials, Vol 2019 (2019) |
| ISSN: | 1687-4110 |
| DOI: | 10.1155/2019/3676384 |
| Popis: | Bisphenol A (BPA) is used in a wide variety of consumer products owing to its beneficial properties of optical clarity, shatter resistance, and heat resistance. However, leached BPA has been shown to disturb the endocrine system and could cause cancer even at low concentrations, which has led to public concern. To reduce the toxic effects caused by BPA, it is important to monitor the BPA levels and its presence in products in a simple, rapid, and on-site manner. Here, we propose a new colorimetric strategy for the simple and rapid detection of BPA employing a DNA aptamer, a cationic surfactant, and gold nanoparticles (AuNPs). Using the developed system, the presence of BPA can be successfully determined based simply on a visually detectable color change from red to blue, triggered by aggregate formation of the AuNPs, which can be monitored even with the naked eye. Under the optimized conditions, this system could detect BPA with excellent selectivity and sensitivity, and its high performance was validated in the receipt obtained from local market and BPA-spiked tap water samples, ensuring its practical applicability. Moreover, the limit of the detection of the system was determined to be 97 nM, which is below the current tolerable daily intake level, demonstrating its suitability for toxicity assessment and on-site quality control in a more economical manner when compared with conventional methods. |
| Databáze: | OpenAIRE |
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