Head and Neck Sinus Histiocytosis with Massive Lymphadenopathy Radiology–Pathology Correlation
| Autor: | Daniel Thomas Ginat, Sandeep Gurbuxani, Vincent Cracolici |
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| Rok vydání: | 2018 |
| Předmět: |
Sine qua non Radiology-Pathology
Male 0301 basic medicine medicine.medical_specialty Pathology Subcapsular Sinus Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine medicine Humans Child Head and neck Histiocyte CD68 business.industry Sinus Histiocytosis with Massive Lymphadenopathy medicine.disease Emperipolesis Histiocytosis 030104 developmental biology Oncology Otorhinolaryngology 030220 oncology & carcinogenesis Radiology Histiocytosis Sinus business |
| Zdroj: | Head and Neck Pathology. 13:656-660 |
| ISSN: | 1936-0568 |
| DOI: | 10.1007/s12105-018-0941-3 |
| Popis: | Sinus histiocytosis with massive lymphadenopathy, or Rosai-Dorfman disease, is a rare, benign type of non-Langerhans cell histiocytosis. The radiological findings are often nonspecific, potentially mimicking malignancies. The diagnosis is ultimately made based on pathology, in which the lymph nodes are characterized by a dilated subcapsular sinus filled with histiocytes that can exhibit emperipolesis. Immunohistochemically, the histiocytes are variably CD68 positive and reliably negative for CD1a. The features of head and neck sinus histiocytosis with massive lymphadenopathy are exemplified in this radiology-pathology correlation sine qua non article. |
| Databáze: | OpenAIRE |
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