Influence of chorionicity on perinatal outcome in a large cohort of Danish twin pregnancies
| Autor: | Birgit Bødker, Helle Zingenberg, Helle Mogensen, F. S. Jørgensen, Anna Oldenburg, A. Holmskov, Line Rode, L. Sperling, Steen Rasmussen, Torben Larsen, Olav Bjørn Petersen, Helle Larsen, I. Stornes, Lone Laursen, Ann Tabor, Lillian Skibsted, V. Ersbak |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Adult
medicine.medical_specialty endocrine system Denmark Twins Gestational Age Sensitivity and Specificity Ultrasonography Prenatal Cohort Studies Pregnancy medicine Twins Dizygotic Humans Radiology Nuclear Medicine and imaging Fetal Death Twin Pregnancy reproductive and urinary physiology Perinatal Mortality Retrospective Studies Gynecology Radiological and Ultrasound Technology Obstetrics business.industry urogenital system Incidence (epidemiology) Infant Newborn Pregnancy Outcome Obstetrics and Gynecology Gestational age Retrospective cohort study General Medicine Chorion Twins Monozygotic medicine.disease Fetal Diseases Reproductive Medicine Cohort embryonic structures Gestation Female business Cohort study |
| Zdroj: | Oldenburg, A M, Rode, L, Bødker, M L B, Ersbak, V, Holmskov, A, Jørgensen, F S, Larsen, H, Larsen, T, Laursen, L, Mogensen, H, Petersen, O B, Rasmussen, S, Skibsted, L H, Sperling, L, Stornes, I, Zingenberg, H J & Tabor, A 2012, ' Influence of chorionicity on perinatal outcome in a large cohort of Danish twin pregnancies ', Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, vol. 39, no. 1, pp. 69-74 . https://doi.org/10.1002/uog.10057 |
| Popis: | Objective To assess outcome in twin pregnancies according to chorionicity. Methods A cohort was retrieved from local ultrasound databases at 14 obstetric departments in Denmark, comprising all twin pregnancies with two live fetuses scanned between weeks 11 and 14 in the period 1 January 2004 to 31 December 2006. Outcome data were retrieved from the National Board of Health. Results Among 2038 twin pregnancies, 1757 (86.2%) were dichorionic (DC) and 281 (13.8%) were monochorionic diamniotic (MC). In MC pregnancies, the rate of spontaneous fetal loss in both second and third trimesters was more than threefold higher than the comparable rate in DC pregnancies: 6.0% vs. 1.9% for at least one fetus in the second trimester (P < 0.001) and 2.1% vs. 0.7% in the third trimester (P = 0.03). In 98.4% of DC pregnancies and in 91.1% of MC pregnancies, at least one infant was liveborn. Amongst pregnancies with two live fetuses at 24 weeks, the proportion with two live infants at 28 days after delivery was 97.5% and 95.1%, respectively. Conclusions The increased incidence of fetal loss in MC pregnancies compared with DC pregnancies predominantly occurs before 24 weeks' gestation. After this stage, although the risk of intrauterine fetal death is still higher in MC than in DC pregnancies, if both fetuses are alive at 24 weeks, the chance of a woman having two live infants 1 month after delivery is similar in MC and DC pregnancies. Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd. |
| Databáze: | OpenAIRE |
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