Efficacy of Pulsed Radiofrequency in Herpetic Neuralgia
| Autor: | Heng Ching Lin, Ying Chin Lin, Yuan Kao, Wen Pei Chang, Jui Chen Tsai, Ka Wai Tam, Shu Fen Chen, Chia Hui Wang, Chih Yin Wu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Neuralgia Postherpetic Cochrane Library Herpes Zoster law.invention 03 medical and health sciences 0302 clinical medicine Quality of life Randomized controlled trial 030202 anesthesiology law Internal medicine medicine Humans Randomized Controlled Trials as Topic Postherpetic neuralgia business.industry Pulsed radiofrequency medicine.disease Confidence interval Pulsed Radiofrequency Treatment Anesthesiology and Pain Medicine Meta-analysis Neuralgia Neurology (clinical) business 030217 neurology & neurosurgery Shingles |
| Zdroj: | The Clinical Journal of Pain. 36:887-895 |
| ISSN: | 0749-8047 |
| DOI: | 10.1097/ajp.0000000000000867 |
| Popis: | Objectives Herpes zoster and postherpetic neuralgia (PHN) are often refractory to current standard treatments and can reduce patients' quality of life (QoL). Pulsed radiofrequency (PRF) effectively controls intractable neurological pain. The aim of the study was to conduct a systematic review and meta-analysis to evaluate the efficacy of PRF in PHN management. Materials and methods We searched PubMed, Embase, and Cochrane Library for randomized controlled trials (RCTs) published up to October 2019. The primary outcomes were pain levels and rescue analgesia at different postintervention time intervals. The secondary outcomes were QoL and sleep quality. Results We reviewed 6 RCTs involving 420 patients. The meta-analysis revealed that the PRF group exhibited significantly lower pain scores in PHN than did the control group at 2 to 3 days (weighted mean differences [WMD]=-2.82; 95% confidence interval [CI]: -5.08 to -0.55), 1 week (WMD=-2.95; 95% CI: -4.53 to -1.37), 2 weeks (WMD=-3.17; 95% CI: -4.11 to -2.23), 4 weeks (WMD=-2.59; 95% CI: -3.40 to -1.79), 8 weeks (WMD=-3.02; 95% CI: -4.17 to -1.88), and 6 months (WMD=-1.94; 95% CI: -2.85 to -1.03). After intervention, QoL was significantly higher in the PRF group than in the control group. No major complications were reported. Discussion PRF safely and effectively reduced pain scores and improved QoL in patients with herpes zoster in the cervical to lumbosacral areas. PRF could be considered during refractory PHN treatment. Future studies require standardized PRF settings and outcome assessment tools, including physical and emotional function assessments. |
| Databáze: | OpenAIRE |
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