Analysis of corneal densitometry and endothelial morphometry in patients with psoriasis
| Autor: | Mustafa Tosun, Erman Bozali, Anıl Selim Apa, Duygu Yalinbas Yeter |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Corneal endothelium
medicine.medical_specialty genetic structures Scheimpflug principle Biophysics Dermatology Cornea Psoriasis Area and Severity Index Ophthalmology Psoriasis medicine Humans Pharmacology (medical) In patient Prospective Studies Photosensitizing Agents medicine.diagnostic_test business.industry Corneal Topography medicine.disease eye diseases Cross-Sectional Studies Photochemotherapy Oncology Eye examination sense organs Densitometry business Ocular surface |
| Zdroj: | Photodiagnosis and Photodynamic Therapy. 36:102522 |
| ISSN: | 1572-1000 |
| DOI: | 10.1016/j.pdpdt.2021.102522 |
| Popis: | To evaluate corneal endothelial properties and corneal densitometry values in patients with psoriasis and to compare the results with those of healthy controls.This prospective, comparative, and cross-sectional study included 106 eyes of 53 patients who were diagnosed with psoriasis and 106 eyes of 53 age-gender matched healthy controls. All patients were evaluated in terms of ocular surface tests such as Schirmer-1 and tear break-up time (TBUT). Corneal endothelial measurements were performed using noncontact specular microscopy. Corneal tomographic and densitometric measurements were obtained using the Scheimpflug imaging system. Measurements were also evaluated according to the psoriasis area and severity index (PASI) score.The mean TBUT and Schirmer 1 test values were significantly lower in the psoriasis group than in the healthy controls (p = 0.02, p 0.001, respectively). While the mean endothelial cell density was significantly lower in patients with psoriasis than the healthy controls (2389.9±314.9 cells/mmA regular eye examination is crucial in patients with psoriasis because corneal structural and functional changes, particularly endothelial alterations, are of utmost importance in planning intraocular surgeries in patients with psoriasis. |
| Databáze: | OpenAIRE |
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