Association between high levels of comorbid anxiety and depressive symptoms and decreased likelihood of birth without intervention:A longitudinal prospective cohort study

Autor: Lianne P. Hulsbosch, Myrthe G. B. M. Boekhorst, Paul Lodder, Eva S. Potharst, Ivan Nyklíček, Veerle Bergink, S. Guid Oei, Corine J. M. Verhoeven, Victor J. M. Pop
Přispěvatelé: Medical and Clinical Psychology, Department of Methodology and Statistics, Midwifery Science, APH - Quality of Care, Amsterdam Reproduction & Development (AR&D)
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Hulsbosch, L P, Boekhorst, M G B M, Lodder, P, Potharst, E S, Nyklíček, I, Bergink, V, Oei, S G, Verhoeven, C J M & Pop, V J M 2022, ' Association between high levels of comorbid anxiety and depressive symptoms and decreased likelihood of birth without intervention : A longitudinal prospective cohort study ', BJOG: An International Journal of Obstetrics & Gynaecology . https://doi.org/10.1111/1471-0528.17273
BJOG: An International Journal of Obstetrics and Gynaecology, 130(5), 495-505. Wiley-Blackwell
BJOG: An International Journal of Obstetrics & Gynaecology. Wiley Online Library
ISSN: 1470-0328
DOI: 10.1111/1471-0528.17273
Popis: ObjectiveTo assess the association between trajectories of comorbid anxiety and depressive (CAD) symptoms assessed in each pregnancy trimester and physiological birth.DesignLarge longitudinal prospective cohort study with recruitment between January 2013 and September 2014.SettingPrimary care, in the Netherlands.PopulationDutch-speaking pregnant women with gestational age at birth ≥37 weeks, and without multiple pregnancy, severe psychiatric disorder or chronic disease history.MethodsPregnancy-specific anxiety and depressive symptoms were measured prospectively in each trimester of pregnancy using the negative affect subscale of the Tilburg Pregnancy Distress Scale and Edinburgh (Postnatal) Depression Scale. Data on physiological birth were obtained from obstetric records. Multivariate growth mixture modelling was performed in MPLUS to determine longitudinal trajectories of CAD symptoms. Multiple logistic regression analysis was used to examine the association between trajectories and physiological birth.Main outcome measuresTrajectories of CAD symptoms and physiological birth.ResultsSeven trajectories (classes) of CAD symptoms were identified in 1682 women and subsequently merged into three groups: group 1—persistently low levels of symptoms (reference class 1; 79.0%), group 2—intermittently high levels of symptoms (classes 3, 6 and 7; 11.2%), and group 3—persistently high levels of symptoms (classes 2, 4 and 5; 9.8%). Persistently high levels of CAD symptoms (group 3) were associated with a lower likelihood of physiological birth (odds ratio 0.67, 95% confidence interval 0.47–0.95, P = 0.027) compared with the reference group (persistently low levels of symptoms), after adjusting for confounders.ConclusionsThis study is the first showing evidence that persistently high CAD levels, assessed in each pregnancy trimester, are associated with a lower likelihood of physiological birth.
Databáze: OpenAIRE
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